In the 10th episode of season 19, which has already screened in the U.S, Carl Carlson tells Homer that former Argentine President Juan Peron was a dictator, adding "When he disappeared you, you stayed disappeared."
"Of course, his wife was Madonna," Lenny Leonard says in reference to the singer-actress' role as Eva Peron in "Evita."
However, it wasn't the Peron regime but the 1976-83 military dictatorship that followed his rule that has been blamed for the disappearance of 30,000 citizens.
The episode isn't skedded to air until June or July on Telefe and Canal Fox in Argentina.
But the segment on YouTube had an estimated 12,000 viewings in Argentina over the weekend.
Lorenzo Pepe, a former congressman and now secretary general of the National Institute of Juan Peron, called on national broadcasting regulator Comfer to intervene.
It isn't clear what action Comfer could take. A spokesman for the regulator said censorship wasn't an option for "The Simpsons," which for years has been a top-rated import in Argentina.